Document Details

Document Type : Thesis 
Document Title :
ANTIMICROBIAL ACTIVITY OF MARINE MACROALGAE FROM THE COAST OF JEDDAH, SAUDI ARABIA
فعالية المضادات الميكروبية للطحالب البحرية الكبيرة من ساحل مدينة جدة، المملكة العربية السعودية
 
Subject : Faculty of Sciences 
Document Language : Arabic 
Abstract : Marine algae are known as a potential source of bioactive compounds. In the present study, marine macroalgae belong to Chlorophyta, Phaeophyta and Rhodophyta were collected from the coastal area of the Red Sea of Jeddah, Saudi Arabia. The phytochemical analyses of these algae were investigated. Algae were extracted in different solvents and tested for their antimicrobial activity against pathogenic bacteria and fungi by using the agar diffusion method. All the extracts, in particular brown and green algae exhibited the highest antimicrobial activity. The most effective extracts were selected to study their effect on the cell wall of some bacteria. The toxicity of some extracts was studied by using the brine shrimp lethality for larvae (nauplii). The active compounds with the highest antibacterial activity of algal extract were isolated and purified by column chromatography and thin layer chromatography. The isolated fractions were identified by using gas chromatograph-mass and 13C-NMR spectrometers. The most active substances isolated from the algal extract were fucoxanthin and fucosterol and they showed a potent antimicrobial activity. The results indicated that marine macroalgae extracts may be useful in order to find alternative drugs and promising source of pharmaceutical agents. 
Supervisor : Prof. Dr. Hanan Hafez Omar 
Thesis Type : Master Thesis 
Publishing Year : 1438 AH
2017 AD 
Co-Supervisor : Dr. Molouk Mohamed Al-Khazan 
Added Date : Sunday, June 11, 2017 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سخاء طلال سمكرىSamkari, Sakaa TalalResearcherMaster 

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